Scientists discuss in 'The difficulty with localization of rectal cancer after neoadjuvant chemoradiation therapy' new findings in rectal cancer. "Neoadjuvant chemoradiation therapy (NCRT) has become the standard treatment for locally advanced rectal cancer. Subsequent downstaging can make identification of the primary tumor challenging," scientists in the United States report (see also Rectal Cancer).
"Complete pathologic response rates of 8 per cent to 27 per cent are seen with current NCRT regimen. Two patients were referred to our institution after NCRT and subsequent low anterior resection in whom no residual cancer was found in the resected specimen but who manifested …
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